U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dpr11 defective proboscis extension response 11 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40800, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dpr11provided by FlyBase
    Official Full Name
    defective proboscis extension response 11provided by FlyBase
    Primary source
    FLYBASE:FBgn0053202
    Locus tag
    Dmel_CG33202
    See related
    AllianceGenome:FB:FBgn0053202
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH22307; CG15181; CG15182; CG15183; CG31309; CG33202; CT35098; Dmel\CG33202; Dpr-11; Dpr11
    Summary
    Involved in establishment of synaptic specificity at neuromuscular junction; photoreceptor cell axon guidance; and regulation of neuromuscular junction development. Located in neuron projection membrane. Is expressed in cell body rind of adult medulla; larval ventral nerve cord; medulla layer; and photoreceptor cell R7. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See dpr11 in Genome Data Viewer
    Location:
    83F1-83F4; 3-47.5 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6529169..6593330, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2354891..2419052, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:Methionine-CAT 1-5 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46132 Neighboring gene PFTAIRE-interacting factor 2 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46131 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The development and function of neuronal subtypes processing color and skylight polarization in the optic lobes of Drosophila melanogaster. Sancer G, et al. Arthropod Struct Dev, 2021 Mar. PMID 33618155
    2. Phenotype of the Triplo-lethal locus of Drosophila melanogaster and its suppression by hyperoxia. Smoyer LK, et al. Genet Res, 2003 Dec. PMID 15134195
    3. Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Cheng S, et al. Elife, 2019 Jan 28. PMID 30688651, Free PMC Article
    4. Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits. Menon KP, et al. Elife, 2019 Nov 6. PMID 31692445, Free PMC Article
    5. Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits. Xu S, et al. Neuron, 2018 Dec 19. PMID 30467079, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Interactions between Dpr11 and DIP-gamma control selection of amacrine neurons in Drosophila color vision circuits.
      Title: Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits.
    2. study provides evidence that DIPgamma in yDm8 neurons and Dpr11 in yR7 photpreceptors instruct synaptic partner matching
      Title: Coordination between stochastic and deterministic specification in the Drosophila visual system.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of synaptic specificity at neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in photoreceptor cell axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of neuromuscular junction development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    defective proboscis extension response 11
    Names
    CG33202-PB
    CG33202-PC
    dpr11-PB
    dpr11-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6529169..6593330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275391.1 → NP_001262320.1  defective proboscis extension response 11, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262320.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRE6, Q9VI28
      Conserved Domains (4) summary
      smart00408
      Location:234 → 311
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:227 → 320
      IG_like; Immunoglobulin like
      pfam07679
      Location:125 → 216
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:127 → 217
      Ig; Immunoglobulin domain

    2. NM_176409.2 → NP_788586.1  defective proboscis extension response 11, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788586.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRE6, Q9VI28
      Related
      FBpp0081202
      Conserved Domains (4) summary
      smart00408
      Location:234 → 311
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:227 → 320
      IG_like; Immunoglobulin like
      pfam07679
      Location:125 → 216
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:127 → 217
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRE6 Q8MRE6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools