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    GstD9 Glutathione S transferase D9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41502, updated on 17-Dec-2024

    Summary

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    Official Symbol
    GstD9provided by FlyBase
    Official Full Name
    Glutathione S transferase D9provided by FlyBase
    Primary source
    FLYBASE:FBgn0038020
    Locus tag
    Dmel_CG10091
    See related
    AllianceGenome:FB:FBgn0038020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10091; Dmel\CG10091; DmGstd9; DmGSTD9; GST-D9; gstd9; gstD9; GSTD9
    Summary
    Enables glutathione transferase activity. Involved in glutathione metabolic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See GstD9 in Genome Data Viewer
    Location:
    87B8-87B8; 3-52 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12366163..12367564, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8191885..8193286, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Tim17a1 Neighboring gene Glutathione S transferase D10 Neighboring gene Glutathione S transferase D1 Neighboring gene long non-coding RNA:CR46015

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila. Yin Y, et al. Cell Death Dis, 2022 Aug 6. PMID 35933423, Free PMC Article
    2. Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila. Brown EB, et al. G3 (Bethesda), 2020 Apr 9. PMID 32024668, Free PMC Article
    3. Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan. Bhide S, et al. Aging Cell, 2018 Jun. PMID 29575479, Free PMC Article
    4. Mitogen-activated protein kinase p38b interaction with delta class glutathione transferases from the fruit fly, Drosophila melanogaster. Wongtrakul J, et al. J Insect Sci, 2012. PMID 23438069, Free PMC Article
    5. Bowman-Birk inhibitor affects pathways associated with energy metabolism in Drosophila melanogaster. Li HM, et al. Insect Mol Biol, 2010 Jun 1. PMID 20113373

    See all (68) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutathione metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    glutathione S transferase D9
    Names
    CG10091-PA
    CG10091-PB
    GstD9-PA
    GstD9-PB
    NP_001287303.1
    NP_650181.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12366163..12367564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141924.2 → NP_650181.1  glutathione S transferase D9, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650181.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E4NKK7, Q9VGA0
      Related
      FBpp0082078
      Conserved Domains (3) summary
      cd03177
      Location:89 → 207
      GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
      COG0625
      Location:4 → 187
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03045
      Location:2 → 75
      GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...

    2. NM_001300374.1 → NP_001287303.1  glutathione S transferase D9, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E4NKK7, Q9VGA0
      Conserved Domains (3) summary
      cd03177
      Location:89 → 207
      GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
      COG0625
      Location:4 → 187
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03045
      Location:2 → 75
      GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGA0 Q9VGA0

    Gene LinkOut

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