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    GstD11 Glutathione S transferase D11 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41512, updated on 17-Dec-2024

    Summary

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    Official Symbol
    GstD11provided by FlyBase
    Official Full Name
    Glutathione S transferase D11provided by FlyBase
    Primary source
    FLYBASE:FBgn0038029
    Locus tag
    Dmel_CG17639
    See related
    AllianceGenome:FB:FBgn0038029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE72392; cg17639; CG17639; Dmel\CG17639; DmGSTD11; gstd11; GSTD11
    Summary
    Enables glutathione peroxidase activity and glutathione transferase activity. Involved in glutathione metabolic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See GstD11 in Genome Data Viewer
    Location:
    87B9-87B9; 3-52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12383336..12385624)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8209058..8211346)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Glutathione S transferase D8 Neighboring gene uncharacterized protein Neighboring gene Sol1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitogen-activated protein kinase p38b interaction with delta class glutathione transferases from the fruit fly, Drosophila melanogaster. Wongtrakul J, et al. J Insect Sci, 2012. PMID 23438069, Free PMC Article
    2. Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits. Godfrey RK, et al. Acta Neuropathol Commun, 2023 Oct 20. PMID 37864255, Free PMC Article
    3. Expression Patterns of Drosophila Melanogaster Glutathione Transferases. Gonis E, et al. Insects, 2022 Jul 7. PMID 35886788, Free PMC Article
    4. Molecular Profiling of the Drosophila Antenna Reveals Conserved Genes Underlying Olfaction in Insects. Mohapatra P, et al. G3 (Bethesda), 2019 Nov 5. PMID 31527046, Free PMC Article
    5. Evolutionary and structural analyses of GDAP1, involved in Charcot-Marie-Tooth disease, characterize a novel class of glutathione transferase-related genes. Marco A, et al. Mol Biol Evol, 2004 Jan. PMID 14595091

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glutathione peroxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutathione metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    glutathione S transferase D11
    Names
    CG17639-PA
    CG17639-PB
    GstD11-PA
    GstD11-PB
    NP_001138040.1
    NP_650183.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12383336..12385624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141926.2 → NP_650183.1  glutathione S transferase D11, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650183.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXQ9, Q9VG90
      Related
      FBpp0082048
      Conserved Domains (2) summary
      cd03177
      Location:91 → 210
      GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
      cd03045
      Location:4 → 77
      GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...

    2. NM_001144568.2 → NP_001138040.1  glutathione S transferase D11, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138040.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0S9
      Conserved Domains (2) summary
      cd03177
      Location:112 → 231
      GST_C_Delta_Epsilon; C-terminal, alpha helical domain of Class Delta and Epsilon Glutathione S-transferases
      cd03045
      Location:25 → 98
      GST_N_Delta_Epsilon; GST_N family, Class Delta and Epsilon subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z0S9 B7Z0S9
    Q8SXQ9 Q8SXQ9

    Gene LinkOut

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