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    CG12402 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41714, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12402provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038202
    Locus tag
    Dmel_CG12402
    See related
    AllianceGenome:FB:FBgn0038202
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12402; FBXL11
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12402 in Genome Data Viewer
    Location:
    88A8-88A8; 3-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14104488..14108321, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9930210..9934043, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46531 Neighboring gene Pyrokinin 1 receptor Neighboring gene antisense RNA:CR44237 Neighboring gene Odorant receptor 88a Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved F-box gene with unusual transcript localization. Das T, et al. Dev Genes Evol, 2002 Apr. PMID 11976951
    2. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014
    3. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
    4. Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. Roberts DM, et al. PLoS One, 2012. PMID 22359584, Free PMC Article
    5. Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development. Ou CY, et al. Trends Genet, 2003 Jul. PMID 12850443

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12402-PA
    CG12402-PB
    CG12402-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14104488..14108321 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142078.3 → NP_650335.1  uncharacterized protein Dmel_CG12402, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650335.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFN3
      Related
      FBpp0082374
      Conserved Domains (4) summary
      cd09293
      Location:430 → 595
      AMN1; Antagonist of mitotic exit network protein 1
      cd00116
      Location:297 → 482
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:412 → 437
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam00646
      Location:75 → 117
      F-box; F-box domain

    2. NM_001275629.1 → NP_001262558.1  uncharacterized protein Dmel_CG12402, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262558.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHI0
      Conserved Domains (4) summary
      cd09293
      Location:430 → 595
      AMN1; Antagonist of mitotic exit network protein 1
      cd00116
      Location:297 → 482
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:412 → 437
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam00646
      Location:75 → 117
      F-box; F-box domain

    3. NM_001316552.1 → NP_001303481.1  uncharacterized protein Dmel_CG12402, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GUT7
      Conserved Domains (4) summary
      cd09293
      Location:430 → 595
      AMN1; Antagonist of mitotic exit network protein 1
      cd00116
      Location:297 → 482
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:412 → 437
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam00646
      Location:75 → 117
      F-box; F-box domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KHI0 A0A0B4KHI0
    A0A126GUT7 A0A126GUT7
    Q9VFN3 Q9VFN3

    Gene LinkOut

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