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    fid fire dancer [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fidprovided by FlyBase
    Official Full Name
    fire dancerprovided by FlyBase
    Primary source
    FLYBASE:FBgn0259146
    Locus tag
    Dmel_CG42261
    See related
    AllianceGenome:FB:FBgn0259146
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14541; CG42261; CG8968; Dmel\CG42261
    Old locus tag
    Dmel_CG14541; Dmel_CG8968
    Summary
    Predicted to enable tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be active in cytoplasm and nucleus. Orthologous to human TRMT9B (tRNA methyltransferase 9B (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fid in Genome Data Viewer
    Location:
    96F9-96F9; 3-89 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25970080..25982736)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21795802..21808458)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene bride of sevenless Neighboring gene Neurofibromin 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function. Hogan CA, et al. EMBO Rep, 2023 Oct 9. PMID 37642556, Free PMC Article
    2. Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila. Haag-Liautard C, et al. Nature, 2007 Jan 4. PMID 17203060
    3. Neuronal identity defines α-synuclein and tau toxicity. Praschberger R, et al. Neuron, 2023 May 17. PMID 36948206, Free PMC Article
    4. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    5. Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model. Voutyraki C, et al. Proc Natl Acad Sci U S A, 2023 Aug 15. PMID 37549261, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA wobble uridine modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    fire dancer
    Names
    CG42261-PB
    fid-PB
    NP_651453.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25970080..25982736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143196.3 → NP_651453.3  fire dancer [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651453.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBJ3
      Conserved Domains (1) summary
      pfam08241
      Location:167 → 257
      Methyltransf_11; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBJ3 Q9VBJ3

    Gene LinkOut

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