Ets65A Ets at 65A [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ets65Aprovided by FlyBase
Official Full Name: Ets at 65Aprovided by FlyBase
Primary source: FLYBASE:FBgn0005658
Locus tag: Dmel_CG7018
See related: AllianceGenome:FB:FBgn0005658
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13294; CG6882; CG7018; D-ets-3; D-Ets-3; Dmel\CG7018; Ets; Ets3; ETS3; ets65A; Ets65a
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including CNS glial cell; central brain primordium; embryonic antennal sense organ; ganglia; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in blood platelet disease; hereditary lymphedema; myeloid leukemia; and thrombocytopenia. Orthologous to human ERG (ETS transcription factor ERG) and FLI1 (Fli-1 proto-oncogene, ETS transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (6097617..6123913)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (6090717..6117013)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of DNA-templated transcription	NAS Non-traceable Author Statement more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

Names: CG7018-PA; CG7018-PB; CG7018-PC; CG7018-PD; CG7018-PE; Ets65A-PA; Ets65A-PB; Ets65A-PC; Ets65A-PD; Ets65A-PE

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The following sections contain reference sequences that belong to a specific genome build. Explain