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    CG13784 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34003, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13784provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031897
    Locus tag
    Dmel_CG13784
    See related
    AllianceGenome:FB:FBgn0031897
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD10385; Dmel\CG13784
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport; phospholipid translocation; and retrograde transport, endosome to Golgi. Predicted to be located in lysosomal membrane. Predicted to be active in endosome and trans-Golgi network. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; dorsal ectoderm anlage; and mesoderm. Orthologous to human SLC66A2 (solute carrier family 66 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13784 in Genome Data Viewer
    Location:
    27E4-27E5; 2-25 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7204538..7220033, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7204538..7220033, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44989 Neighboring gene mitochondrial translation elongation factor G 1 Neighboring gene Na[+]-driven anion exchanger 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila mitochondrial translation elongation factor G1 contains a nuclear localization signal and inhibits growth and DPP signaling. Trivigno C, et al. PLoS One, 2011 Feb 25. PMID 21364917, Free PMC Article
    2. Steroid hormone control of cell death and cell survival: molecular insights using RNAi. Chittaranjan S, et al. PLoS Genet, 2009 Feb. PMID 19214204, Free PMC Article
    3. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
    4. Identification of conserved transcriptome features between humans and Drosophila in the aging brain utilizing machine learning on combined data from the NIH Sequence Read Archive. Webb JL, et al. PLoS One, 2021. PMID 34379632, Free PMC Article
    5. Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration. Nelson B, et al. Cell Death Differ, 2005 Aug. PMID 15861189

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in phospholipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in lysosomal membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13784-PB
    CG13784-PC
    CG13784-PD
    CG13784-PE
    CG13784-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7204538..7220033 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273245.2 → NP_001260174.1  uncharacterized protein Dmel_CG13784, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260174.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCT0
      Conserved Domains (1) summary
      pfam04193
      Location:185 → 240
      PQ-loop; PQ loop repeat

    2. NM_001273246.2 → NP_001260175.1  uncharacterized protein Dmel_CG13784, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260175.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCE7
      Conserved Domains (1) summary
      pfam04193
      Location:193 → 248
      PQ-loop; PQ loop repeat

    3. NM_001273247.2 → NP_001260176.1  uncharacterized protein Dmel_CG13784, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260176.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEZ6
      Conserved Domains (1) summary
      pfam04193
      Location:193 → 248
      PQ-loop; PQ loop repeat

    4. NM_001042878.4 → NP_001036343.2  uncharacterized protein Dmel_CG13784, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036343.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8S5
      Conserved Domains (1) summary
      pfam04193
      Location:193 → 248
      PQ-loop; PQ loop repeat

    5. NM_164742.3 → NP_723261.1  uncharacterized protein Dmel_CG13784, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723261.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9A4
      Related
      FBpp0079042
      Conserved Domains (1) summary
      pfam04193
      Location:18 → 67
      PQ-loop; PQ loop repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PCE7 M9PCE7
    M9PCT0 M9PCT0
    M9PEZ6 M9PEZ6
    Q0E8S5 Q0E8S5
    Q8T9A4 Q8T9A4
    Q95SN2 Q95SN2

    Gene LinkOut

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