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    CG6204 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42877, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6204provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039165
    Locus tag
    Dmel_CG6204
    See related
    AllianceGenome:FB:FBgn0039165
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6204; GH20028p
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Is expressed in organism. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ZNFX1 (zinc finger NFX1-type containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6204 in Genome Data Viewer
    Location:
    95F1-95F1; 3-84 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24193832..24196880)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20019554..20022602)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene morgana Neighboring gene uncharacterized protein Neighboring gene Structural maintenance of chromosomes 6 Neighboring gene twin Neighboring gene uncharacterized protein Neighboring gene caravaggio Neighboring gene Sp1-like factor for pairing sensitive-silencing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Greene JC, et al. Hum Mol Genet, 2005 Mar 15. PMID 15689351
    2. A map of directional genetic interactions in a metazoan cell. Fischer B, et al. Elife, 2015 Mar 6. PMID 25748138, Free PMC Article
    3. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear RNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6204-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24193832..24196880
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142972.5 → NP_651229.2  uncharacterized protein Dmel_CG6204 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651229.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TZ2, Q9VCB7
      Related
      FBpp0083940
      Conserved Domains (3) summary
      pfam13086
      Location:449 → 679
      AAA_11; AAA domain
      pfam13245
      Location:467 → 513
      AAA_19; Part of AAA domain
      cl22977
      Location:688 → 869
      UvrD_C_2; UvrD-like helicase C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95TZ2 Q95TZ2
    Q9VCB7 Q9VCB7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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