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    CG17896 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 30995, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17896provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0023537
    Locus tag
    Dmel_CG17896
    See related
    AllianceGenome:FB:FBgn0023537
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    153323_at; Dmel\CG17896; EG:171D11.1
    Summary
    Predicted to enable methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity. Predicted to be involved in thymine catabolic process and valine catabolic process. Predicted to be active in mitochondrion. Is expressed in adult head; adult heart; embryonic hindgut; and organism. Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17896 in Genome Data Viewer
    Location:
    1B5-1B5; 1-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (490787..493495, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (384820..387528, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45797 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44891 Neighboring gene uncharacterized protein Neighboring gene silver

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives. Yeramian E, et al. Nucleic Acids Res, 2003 Jul 1. PMID 12824434, Free PMC Article
    2. Identification of Drosophila MicroRNA targets. Stark A, et al. PLoS Biol, 2003 Dec. PMID 14691535, Free PMC Article
    3. X chromosome-linked intellectual disability protein PQBP1 associates with and regulates the translation of specific mRNAs. Wan D, et al. Hum Mol Genet, 2015 Aug 15. PMID 26002102
    4. Identification of Genes Involved in the Differentiation of R7y and R7p Photoreceptor Cells in Drosophila. Earl JB, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972998, Free PMC Article
    5. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyrimidine nucleobase metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in thymine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in thymine metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in valine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in valine metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17896-PA
    CG17896-PB
    NP_569845.2
    NP_726672.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      490787..493495 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130489.3 → NP_569845.2  uncharacterized protein Dmel_CG17896, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569845.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O46056, Q7KW39, Q8T9I0, Q9V408
      UniProtKB/TrEMBL
      I0B1N8
      Related
      FBpp0070087
      Conserved Domains (1) summary
      cd07085
      Location:26 → 502
      ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2

    2. NM_166844.1 → NP_726672.1  uncharacterized protein Dmel_CG17896, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726672.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      I0B1N8
      Related
      FBpp0070088, FBtr0070093
      Conserved Domains (1) summary
      cd07085
      Location:17 → 493
      ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KW39.1 Q7KW39

    Gene LinkOut

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