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    CG10417 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35492, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10417provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033021
    Locus tag
    Dmel_CG10417
    See related
    AllianceGenome:FB:FBgn0033021
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10417; PP2Cg
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Is expressed in organism. Orthologous to human PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10417 in Genome Data Viewer
    Location:
    41E5-41E5; 2-55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5360331..5363104, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1247836..1250609, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR42646 Neighboring gene Intraflagellar transport 20 Neighboring gene Cytochrome c oxidase subunit 4-like Neighboring gene straw

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An RNAi Screen To Identify Protein Phosphatases That Function Within the Drosophila Circadian Clock. Agrawal P, et al. G3 (Bethesda), 2016 Dec 7. PMID 27784754, Free PMC Article
    2. mTORC1-chaperonin CCT signaling regulates m(6)A RNA methylation to suppress autophagy. Tang HW, et al. Proc Natl Acad Sci U S A, 2021 Mar 9. PMID 33649236, Free PMC Article
    3. The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Ashton-Beaucage D, et al. Cell, 2010 Oct 15. PMID 20946983
    4. Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. Myster SH, et al. Genetics, 2004 Feb. PMID 15020470, Free PMC Article
    5. Transgenic Drosophila lines for LexA-dependent gene and growth regulation. Chang KR, et al. G3 (Bethesda), 2022 Mar 4. PMID 35100369, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10417-PA
    CG10417-PB
    NP_610169.1
    NP_724410.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5360331..5363104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165430.2 → NP_724410.1  uncharacterized protein Dmel_CG10417, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724410.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K4Q5
      UniProtKB/TrEMBL
      E2QC56
      Related
      FBpp0085428
      Conserved Domains (2) summary
      smart00332
      Location:18 → 100
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
      cd00143
      Location:374 → 564
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    2. NM_136325.3 → NP_610169.1  uncharacterized protein Dmel_CG10417, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610169.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K4Q5
      UniProtKB/TrEMBL
      E2QC56
      Related
      FBpp0085427
      Conserved Domains (2) summary
      smart00332
      Location:18 → 100
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
      cd00143
      Location:374 → 564
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E2QC56 E2QC56
    Q7K4Q5.1 Q7K4Q5

    Gene LinkOut

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