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    bdwf bedwarfed [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42057, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bdwfprovided by FlyBase
    Official Full Name
    bedwarfedprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038472
    Locus tag
    Dmel_CG3995
    See related
    AllianceGenome:FB:FBgn0038472
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3995; Dmel\CG3995
    Summary
    Enables ribosome binding activity. Involved in ribosome localization. Acts upstream of with a positive effect on dendrite arborization. Located in cytosol and nucleoplasm. Is expressed in central brain primordium; embryonic brain; larval dorsal multidendritic neurons; organism; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bdwf in Genome Data Viewer
    Location:
    89E10-89E10; 3-59 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17041896..17043136, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12867618..12868858, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA methyltransferase 7-32 Neighboring gene Protein associated with topo II related - 1 Neighboring gene Daughters against dpp

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction. Pradhan SJ, et al. J Cell Sci, 2012 Dec 15. PMID 23097047, Free PMC Article
    2. The Zinc-BED Transcription Factor Bedwarfed Promotes Proportional Dendritic Growth and Branching through Transcriptional and Translational Regulation in Drosophila. Bhattacharjee S, et al. Int J Mol Sci, 2023 Mar 28. PMID 37047316, Free PMC Article
    3. The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases. Aravind L. Trends Biochem Sci, 2000 Sep. PMID 10973053
    4. Local Microtubule and F-Actin Distributions Fully Constrain the Spatial Geometry of Drosophila Sensory Dendritic Arbors. Nanda S, et al. Int J Mol Sci, 2023 Apr 4. PMID 37047715, Free PMC Article
    5. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_positive_effect dendrite arborization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosome localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bedwarfed
    Names
    CG3995-PA
    bdwf-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17041896..17043136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142334.3 → NP_650591.1  bedwarfed [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650591.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MR15, Q9VEP0
      Related
      FBpp0082869
      Conserved Domains (2) summary
      pfam02892
      Location:6 → 47
      zf-BED; BED zinc finger
      cl23759
      Location:73 → 143
      GT1; GT1, myb-like, SANT family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MR15 Q8MR15
    Q9VEP0 Q9VEP0

    Gene LinkOut

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