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    RDN18-1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164923, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RDN18-1
    Primary source
    SGD:S000006482
    Locus tag
    YNCL0016C
    See related
    AllianceGenome:SGD:S000006482
    Gene type
    rRNA
    RNA name
    18S ribosomal RNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables translation elongation factor binding activity. Involved in formation of translation preinitiation complex; translation reinitiation; and translational elongation. Part of cytosolic small ribosomal subunit. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RDN18-1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (455933..457732, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene 5.8S ribosomal RNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene 5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection. Dong J, et al. Genes Dev, 2008 Aug 15. PMID 18708582, Free PMC Article
    2. Yeast 18 S rRNA is directly involved in the ribosomal response to stringent AUG selection during translation initiation. Nemoto N, et al. J Biol Chem, 2010 Oct 15. PMID 20699223, Free PMC Article
    3. Two nucleotide substitutions in the A-site of yeast 18S rRNA affect translation and differentiate the interaction of ribosomes with aminoglycoside antibiotics. Tselika S, et al. Biochimie, 2008 Jun. PMID 18331849
    4. Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome. Velichutina IV, et al. RNA, 2000 Aug. PMID 10943896, Free PMC Article
    5. Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity. Fan-Minogue H, et al. RNA, 2008 Jan. PMID 18003936, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The kinase Rio1 and a ribosome collision-dependent decay pathway survey the integrity of 18S rRNA cleavage.
      Title: The kinase Rio1 and a ribosome collision-dependent decay pathway survey the integrity of 18S rRNA cleavage.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • 18S ribosomal RNA (18S rRNA); component of the small (40S) ribosomal subunit; involved in codon recognition by tRNAs or the release factor eRF1 (Sup45p); encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables translation elongation factor binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in formation of translation preinitiation complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation reinitiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      455933..457732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132213.1 RNA Sequence

      Status: REVIEWED

    Gene LinkOut

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    Research Materials