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    PRM5 pheromone-regulated protein PRM5 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854689, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PRM5
    Official Full Name
    pheromone-regulated protein PRM5
    Primary source
    SGD:S000001379
    Locus tag
    YIL117C
    See related
    AllianceGenome:SGD:S000001379; FungiDB:YIL117C; VEuPathDB:YIL117C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be located in membrane. Predicted to be active in cellular bud neck and fungal-type vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PRM5 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (140613..141569, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Rpi1p Neighboring gene Rho family GTPase RHO3 Neighboring gene histidinol-phosphate transaminase Neighboring gene FG-nucleoporin NUP159

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway. Jung US, et al. Mol Microbiol, 1999 Dec. PMID 10594829
    2. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. Heiman MG, et al. J Cell Biol, 2000 Oct 30. PMID 11062271, Free PMC Article
    3. New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae. Vandermeulen MD, et al. Genetics, 2020 Sep. PMID 32665277, Free PMC Article
    4. A novel connection between the Cell Wall Integrity and the PKA pathways regulates cell wall stress response in yeast. García R, et al. Sci Rep, 2017 Jul 18. PMID 28720901, Free PMC Article
    5. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular bud neck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in fungal-type vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pheromone-regulated protein PRM5
    NP_012149.1
    • Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      140613..141569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179465.1 → NP_012149.1  TPA: pheromone-regulated protein PRM5 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012149.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LTW4, B5VKJ2, D6VVH0, P40476
      UniProtKB/TrEMBL
      N1P4D9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40476.1

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