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    LIN1 U5 snRNP complex subunit LIN1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856561, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LIN1
    Official Full Name
    U5 snRNP complex subunit LIN1
    Primary source
    SGD:S000001199
    Locus tag
    YHR156C
    See related
    AllianceGenome:SGD:S000001199; FungiDB:YHR156C; VEuPathDB:YHR156C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SNU40
    Summary
    Located in chromatin and nucleus. Part of U5 snRNP. Orthologous to human CD2BP2 (CD2 cytoplasmic tail binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See LIN1 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (411384..412406, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Lam1p Neighboring gene ncRNA Neighboring gene Rec104p Neighboring gene Kel1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Incorporating functional inter-relationships into protein function prediction algorithms. Pandey G, et al. BMC Bioinformatics, 2009 May 12. PMID 19435516, Free PMC Article
    2. Proteins interacting with Lin 1p, a putative link between chromosome segregation, mRNA splicing and DNA replication in Saccharomyces cerevisiae. Bialkowska A, et al. Yeast, 2002 Nov. PMID 12402242
    3. Bayesian Markov Random Field analysis for protein function prediction based on network data. Kourmpetis YA, et al. PLoS One, 2010 Feb 24. PMID 20195360, Free PMC Article
    4. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Häcker I, et al. Nat Struct Mol Biol, 2008 Nov. PMID 18953335
    5. Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. Stevens SW, et al. RNA, 2001 Nov. PMID 11720284, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U5 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    U5 snRNP complex subunit LIN1
    NP_012026.1
    • Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      411384..412406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179287.1 → NP_012026.1  TPA: U5 snRNP complex subunit LIN1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012026.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLA5, P38852
      UniProtKB/TrEMBL
      A6ZT64, B5VK85, C7GJY2, C8Z9V3, N1P9G9
      Conserved Domains (1) summary
      smart00444
      Location:283 → 340
      GYF; Contains conserved Gly-Tyr-Phe residues
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38852.1

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