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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852126, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000002922
    Locus tag
    YDR514C
    See related
    AllianceGenome:SGD:S000002922; FungiDB:YDR514C; VEuPathDB:YDR514C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable nucleic acid binding activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1471548..1472999, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sdh7p Neighboring gene Emi1p Neighboring gene dithiol glutaredoxin GRX2 Neighboring gene Slf1p Neighboring gene putative glucokinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Development of a multiplexed microfluidic proteomic reactor and its application for studying protein-protein interactions. Tian R, et al. Anal Chem, 2011 Jun 1. PMID 21520965
    2. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
    3. An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking. Arlt H, et al. Traffic, 2011 Nov. PMID 21777356
    4. Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability. Bryant EE, et al. Nucleic Acids Res, 2019 Sep 26. PMID 31350889, Free PMC Article
    5. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_010802.1
    • hypothetical protein that localizes to mitochondria; overexpression affects endocytic protein trafficking; YDR514C has a paralog, GFD2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1471548..1472999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180822.1 → NP_010802.1  TPA: uncharacterized protein YDR514C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010802.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTD5, Q04408
      UniProtKB/TrEMBL
      C7GKU7, C8Z670, G2WBP1, N1P928
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04408.1

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