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    CPP3 cysteine-rich palmitoylated domain-containing protein CPP3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851604, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CPP3
    Official Full Name
    cysteine-rich palmitoylated domain-containing protein CPP3
    Primary source
    SGD:S000007234
    Locus tag
    YDR034W-B
    See related
    AllianceGenome:SGD:S000007234; FungiDB:YDR034W-B; VEuPathDB:YDR034W-B
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in plasma membrane. Is active in cell periphery and vacuolar membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CPP3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (521314..521469)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA-Gln Neighboring gene 3-deoxy-7-phosphoheptulonate synthase ARO3 Neighboring gene mitochondrial 37S ribosomal protein EHD3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming. Zvonarev A, et al. Genes (Basel), 2023 Apr 27. PMID 37239347, Free PMC Article
    2. Palmitoylation of CYSTM (CYSPD) proteins in yeast. Giolito ML, et al. J Biol Chem, 2024 Feb. PMID 38159851, Free PMC Article
    3. Dissection and design of yeast prions. Osherovich LZ, et al. PLoS Biol, 2004 Apr. PMID 15045026, Free PMC Article
    4. CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. Venancio TM, et al. Bioinformatics, 2010 Jan 15. PMID 19933165, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Jacq C, et al. Nature, 1997 May 29. PMID 9169867

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
      Title: The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in vacuolar membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cysteine-rich palmitoylated domain-containing protein CPP3
    NP_010319.3
    • Tail-anchored plasma membrane (PM) protein; C-terminal palmitoylation is required for membrane anchoring and protein stability; PM localization is polarized to the daughter cell; also localizes to the vacuolar membrane; may be involved in response to stress; upregulated by toxic concentrations of heavy metal ions and alkali; contains a conserved cysteine rich palmitoylated domain (CYSPD, aka CYSTM); CPP3 has a paralog, MNC1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      521314..521469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184327.3 → NP_010319.3  TPA: cysteine-rich palmitoylated domain-containing protein CPP3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010319.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS22, Q6Q5X2
      UniProtKB/TrEMBL
      A6ZY02, B3LGN1, C7GQ12, C8Z4V6, G2WAE0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6Q5X2.1

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