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    TIR2 putative GPI-anchored mannoprotein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854174, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TIR2
    Official Full Name
    putative GPI-anchored mannoprotein
    Primary source
    SGD:S000005536
    Locus tag
    YOR010C
    See related
    AllianceGenome:SGD:S000005536; FungiDB:YOR010C; VEuPathDB:YOR010C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SRP2
    Summary
    Predicted to be a structural constituent of cell wall. Involved in cellular response to freezing. Located in cell periphery and fungal-type vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TIR2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (346195..346950, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tir4p Neighboring gene ATP-binding cassette sterol transporter AUS1 Neighboring gene tRNA-Thr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cold-shock induction of a family of TIP1-related proteins associated with the membrane in Saccharomyces cerevisiae. Kowalski LR, et al. Mol Microbiol, 1995 Jan. PMID 7746155
    2. Induction and repression of DAN1 and the family of anaerobic mannoprotein genes in Saccharomyces cerevisiae occurs through a complex array of regulatory sites. Cohen BD, et al. Nucleic Acids Res, 2001 Feb 1. PMID 11160904, Free PMC Article
    3. Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae. Abramova NE, et al. Genetics, 2001 Mar. PMID 11238402, Free PMC Article
    4. Analysis of low temperature-induced genes (LTIG) in wine yeast during alcoholic fermentation. Chiva R, et al. FEMS Yeast Res, 2012 Nov. PMID 22835029
    5. The influence of HMF and furfural on redox-balance and energy-state of xylose-utilizing Saccharomyces cerevisiae. Ask M, et al. Biotechnol Biofuels, 2013 Feb 15. PMID 23409974, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to freezing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative GPI-anchored mannoprotein
    NP_014653.1
    • Putative cell wall mannoprotein; member of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis; TIR2 has a paralog, TIR3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      346195..346950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183429.1 → NP_014653.1  TPA: putative GPI-anchored mannoprotein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014653.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W277, P33890
      UniProtKB/TrEMBL
      B3LJ66, C7GLE2, C8ZHX5
      Conserved Domains (2) summary
      pfam00399
      Location:207 → 223
      PIR; Yeast PIR protein repeat
      pfam00660
      Location:19 → 111
      SRP1_TIP1; Seripauperin and TIP1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P33890.1

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