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    MRPL4 mitochondrial 54S ribosomal protein YmL4 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851160, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRPL4
    Official Full Name
    mitochondrial 54S ribosomal protein YmL4
    Primary source
    SGD:S000004431
    Locus tag
    YLR439W
    See related
    AllianceGenome:SGD:S000004431; FungiDB:YLR439W; VEuPathDB:YLR439W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL29m
    Summary
    A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL47 (mitochondrial ribosomal protein L47). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRPL4 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (1014491..1015450)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ornithine-oxo-acid transaminase Neighboring gene U4/U6-U5 snRNP complex subunit LSM3 Neighboring gene Sec39p Neighboring gene ribosomal 40S subunit protein S1A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial ribosomes of yeast: isolation of individual proteins and N-terminal sequencing. Graack HR, et al. FEBS Lett, 1988 Dec 19. PMID 3060376
    2. Gene MRP-L4, encoding mitochondrial ribosomal protein YmL4, is indispensable for proper non-respiratory cell functions in yeast. Graack HR, et al. Gene, 1995 Jan 11. PMID 7828914
    3. The putative GTPase encoded by MTG3 functions in a novel pathway for regulating assembly of the small subunit of yeast mitochondrial ribosomes. Paul MF, et al. J Biol Chem, 2012 Jul 13. PMID 22621929, Free PMC Article
    4. Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. Gruschke S, et al. J Cell Biol, 2011 Jun 13. PMID 21670217, Free PMC Article
    5. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. Gruschke S, et al. J Biol Chem, 2010 Jun 18. PMID 20404317, Free PMC Article

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL4
    NP_013544.1
    • Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      1014491..1015450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182327.1 → NP_013544.1  TPA: mitochondrial 54S ribosomal protein YmL4 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013544.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7A1V9, D6VZ74, P36517
      UniProtKB/TrEMBL
      B3RHU8, C7GSL6, C8ZE47, G2WJQ0, N1P7G5
      Conserved Domains (1) summary
      cl09943
      Location:68 → 159
      Ribosomal_L29_HIP; Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36517.2

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