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    Rps8 ribosomal protein S8 [ Mus musculus (house mouse) ]

    Gene ID: 20116, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rps8provided by MGI
    Official Full Name
    ribosomal protein S8provided by MGI
    Primary source
    MGI:MGI:98166
    See related
    Ensembl:ENSMUSG00000047675 AllianceGenome:MGI:98166
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    A structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Is expressed in brain; cerebral cortex ventricular layer; and cortical plate. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 565.9), liver E14 (RPKM 526.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rps8 in Genome Data Viewer
    Location:
    4 D1; 4 53.41 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (117011033..117013329, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (117153836..117156132, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene bestrophin 4, pseudogene Neighboring gene polymerase (RNA) II (DNA directed) polypeptide L pseudogene Neighboring gene STARR-seq mESC enhancer starr_11160 Neighboring gene STARR-positive B cell enhancer ABC_E3505 Neighboring gene small nucleolar RNA, C/D box 38A Neighboring gene predicted gene, 22980 Neighboring gene predicted gene, 26330 Neighboring gene small nucleolar RNA, C/D box 55 Neighboring gene kinesin family member 2C Neighboring gene STARR-positive B cell enhancer ABC_E4651 Neighboring gene STARR-positive B cell enhancer ABC_E662 Neighboring gene predicted gene, 25099

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC107577

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein eS8
    Names
    40S ribosomal protein S8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009098.2NP_033124.1  small ribosomal subunit protein eS8

      See identical proteins and their annotated locations for NP_033124.1

      Status: PROVISIONAL

      Source sequence(s)
      AK010650
      Consensus CDS
      CCDS18530.1
      UniProtKB/Swiss-Prot
      P62242, Q8C2G6
      UniProtKB/TrEMBL
      Q497E9, Q5M9L9
      Related
      ENSMUSP00000099757.5, ENSMUST00000102696.5
      Conserved Domains (1) summary
      PTZ00148
      Location:1206
      PTZ00148; 40S ribosomal protein S8; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      117011033..117013329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)