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    Ir11a Ionotropic receptor 11a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32189, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir11aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 11aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030385
    Locus tag
    Dmel_CG15732
    See related
    AllianceGenome:FB:FBgn0030385
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    11a; CG15732; CT35969; DmelIR11a; Dmel\CG15732; IR11a; Q9VYN4_DROME
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Involved in sensory perception of taste. Predicted to be located in membrane. Is expressed in adult abdomen; gustatory receptor neurons; internal compound sense organ; and labellar taste bristle. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir11a in Genome Data Viewer
    Location:
    11A9-11A9; 1-38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12375596..12377755, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12269629..12271788, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Tenascin accessory Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Genetics of Male Pheromone Preference Difference Between Drosophila melanogaster and Drosophila simulans. Shahandeh MP, et al. G3 (Bethesda), 2020 Jan 7. PMID 31748379, Free PMC Article
    2. Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion. Arguello JR, et al. Nat Commun, 2016 Jun 13. PMID 27292132, Free PMC Article
    3. Molecular basis of fatty acid taste in Drosophila. Ahn JE, et al. Elife, 2017 Dec 12. PMID 29231818, Free PMC Article
    4. Combinatorial Pharyngeal Taste Coding for Feeding Avoidance in Adult Drosophila. Chen YD, et al. Cell Rep, 2019 Oct 22. PMID 31644916, Free PMC Article
    5. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of taste IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 11a
    Names
    CG15732-PB
    Ir11a-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12375596..12377755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132567.1 → NP_572795.2  ionotropic receptor 11a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572795.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYN4
      Related
      FBtr0336964
      Conserved Domains (1) summary
      cl21456
      Location:306 → 356
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYN4 Q9VYN4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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