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    CG11777 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36108, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11777provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033527
    Locus tag
    Dmel_CG11777
    See related
    AllianceGenome:FB:FBgn0033527
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE61564; cg11777; Dmel\CG11777
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein polyubiquitination. Predicted to be part of catalytic step 2 spliceosome. Is expressed in organism. Orthologous to human PPIL3 (peptidylprolyl isomerase like 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11777 in Genome Data Viewer
    Location:
    47A9-47A9; 2-62 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10468616..10469643)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6356121..6357148)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene G protein alpha subunit o Neighboring gene Cytochrome P450 49a1 Neighboring gene Chromatin assembly factor 1, p105 subunit Neighboring gene withered Neighboring gene antisense RNA:CR45134 Neighboring gene translin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CAF-1 promotes Notch signaling through epigenetic control of target gene expression during Drosophila development. Yu Z, et al. Development, 2013 Sep. PMID 23942516, Free PMC Article
    2. Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene. Strub BR, et al. Genome, 2008 Jun. PMID 18521119
    3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    4. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
    5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein polyubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11777-PA
    NP_724939.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10468616..10469643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165776.4 → NP_724939.1  uncharacterized protein Dmel_CG11777 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724939.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NN46, Q8MKJ6
      Related
      FBpp0087366
      Conserved Domains (1) summary
      cd01928
      Location:1 → 154
      Cyclophilin_PPIL3_like; Proteins similar to Human cyclophilin-like peptidylprolyl cis- trans isomerase (PPIL3). Members of this family lack a key residue important for cyclosporin binding: the tryptophan residue corresponding to W121 in human hCyP-18a; most members have a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MKJ6 Q8MKJ6

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