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    CG9003 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36244, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9003provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033639
    Locus tag
    Dmel_CG9003
    See related
    AllianceGenome:FB:FBgn0033639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9003; FBXL2
    Summary
    Involved in response to endoplasmic reticulum stress. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in adult head and spermatozoon. Orthologous to human FBXL2 (F-box and leucine rich repeat protein 2) and FBXL20 (F-box and leucine rich repeat protein 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9003 in Genome Data Viewer
    Location:
    48B2-48B4; 2-64 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11641477..11651616, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7528982..7539121, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Enigma Neighboring gene atossa Neighboring gene transfer RNA:Arginine-TCT 1-1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in response to endoplasmic reticulum stress HMP PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9003-PA
    CG9003-PB
    CG9003-PC
    CG9003-PD
    CG9003-PE
    CG9003-PF
    CG9003-PG
    Fbxl5 iron sensing

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11641477..11651616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273973.2 → NP_001260902.1  uncharacterized protein Dmel_CG9003, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260902.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI22
      Conserved Domains (3) summary
      cd09293
      Location:195 → 372
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:120 → 145
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:26 → 69
      F-box-like

    2. NM_001103801.2 → NP_001097271.1  uncharacterized protein Dmel_CG9003, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097271.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYA6
      Conserved Domains (3) summary
      cd09293
      Location:409 → 586
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:334 → 359
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:240 → 285
      F-box-like; F-box-like

    3. NM_001273971.2 → NP_001260900.1  uncharacterized protein Dmel_CG9003, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260900.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEK4
      Conserved Domains (3) summary
      cd09293
      Location:195 → 372
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:120 → 145
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:26 → 71
      F-box-like; F-box-like

    4. NM_001273972.2 → NP_001260901.1  uncharacterized protein Dmel_CG9003, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260901.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEU4
      Conserved Domains (3) summary
      cd09293
      Location:195 → 372
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:120 → 145
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:26 → 71
      F-box-like; F-box-like

    5. NM_001103803.3 → NP_001097273.1  uncharacterized protein Dmel_CG9003, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097273.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI22
      Conserved Domains (3) summary
      cd09293
      Location:195 → 372
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:120 → 145
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:26 → 69
      F-box-like

    6. NM_001103802.2 → NP_001097272.1  uncharacterized protein Dmel_CG9003, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097272.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYA5
      Conserved Domains (3) summary
      cd09293
      Location:184 → 361
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:109 → 134
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:15 → 58
      F-box-like

    7. NM_136845.3 → NP_610689.1  uncharacterized protein Dmel_CG9003, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610689.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8M8
      Related
      FBpp0087190
      Conserved Domains (3) summary
      cd09293
      Location:222 → 399
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:147 → 172
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:53 → 98
      F-box-like; F-box-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEK4 A0A0B4KEK4
    A0A0B4KEU4 A0A0B4KEU4
    A1Z8M8 A1Z8M8
    A8DYA5 A8DYA5
    A8DYA6 A8DYA6
    Q5BI22 Q5BI22

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