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    Phk-3 Pherokine 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37997, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Phk-3provided by FlyBase
    Official Full Name
    Pherokine 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0035089
    Locus tag
    Dmel_CG9358
    See related
    AllianceGenome:FB:FBgn0035089
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE09339; CG9358; DmelCSP3; Dmel\CG9358; PHK-3
    Summary
    Involved in metamorphosis and response to bacterium. Predicted to be located in extracellular space. Is expressed in several structures, including Bolwig organ; cuboidal/columnar epithelium; embryonic head epidermis; embryonic head sensory system; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Phk-3 in Genome Data Viewer
    Location:
    60E11-60E11; 2-107 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24970843..24973207, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20858366..20860730, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene cGAS-like receptor 2 Neighboring gene Ribosomal protein L19 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45252

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome and EST analyses and expression of a gene family with putative functions in insect chemoreception. Zhou JJ, et al. Chem Senses, 2006 Jun. PMID 16581978
    2. Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene. Nishida Y, et al. EMBO J, 1988 Mar. PMID 3135183, Free PMC Article
    3. Pherokine-2 and -3. Sabatier L, et al. Eur J Biochem, 2003 Aug. PMID 12899697
    4. A genomic comparison of faster-sex, faster-X, and faster-male evolution between Drosophila melanogaster and Drosophila pseudoobscura. Musters H, et al. J Mol Evol, 2006 Jun. PMID 16612543
    5. Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia. Abe M, et al. J Exp Biol, 2022 Nov 1. PMID 36226701, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in metamorphosis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular space ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pherokine 3
    Names
    CG9358-PA
    CG9358-PB
    CG9358-PC
    Phk-3-PA
    Phk-3-PB
    Phk-3-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24970843..24973207 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299941.1 → NP_001286870.1  pherokine 3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286870.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0X2
      Conserved Domains (1) summary
      pfam03392
      Location:24 → 115
      OS-D; Insect pheromone-binding family, A10/OS-D

    2. NM_001299942.1 → NP_001286871.1  pherokine 3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0X2
      Conserved Domains (1) summary
      pfam03392
      Location:24 → 115
      OS-D; Insect pheromone-binding family, A10/OS-D

    3. NM_138146.3 → NP_611990.1  pherokine 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611990.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0X2
      Related
      FBpp0072311
      Conserved Domains (1) summary
      pfam03392
      Location:24 → 115
      OS-D; Insect pheromone-binding family, A10/OS-D
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W0X2 Q9W0X2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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