CG1889 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG1889provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0030164
Locus tag: Dmel_CG1889
See related: AllianceGenome:FB:FBgn0030164
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AAF46536; AAN09619; Dmel\CG1889; FBpp0071343; FBpp0071344
Summary: Predicted to enable G protein-coupled receptor binding activity and chitin binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human TNR (tenascin R). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 9A3-9A3; 1-30 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (9965241..9966959)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (9859274..9860992)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	ISS Inferred from Sequence or Structural Similarity more info
enables chitin binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG1889-PA; CG1889-PC; CG1889-PD; CG1889-PE; Fibrinogen-related protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

9965241..9966959

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_132364.4 → NP_572592.1 uncharacterized protein Dmel_CG1889, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_572592.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9W301

Related

FBpp0071343

Conserved Domains (1) summary

cd00087
Location:117 → 329

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
NM_001272463.1 → NP_001259392.1 uncharacterized protein Dmel_CG1889, isoform E [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001259392.1

Status: REVIEWED

UniProtKB/TrEMBL

M9PH45
NM_167208.3 → NP_727376.2 uncharacterized protein Dmel_CG1889, isoform D [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_727376.2

Status: REVIEWED

UniProtKB/TrEMBL

Q8IRM2

Conserved Domains (2) summary

cd00087
Location:123 → 335

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

pfam14389
Location:34 → 80

Lzipper-MIP1; Leucine-zipper of ternary complex factor MIP1
NM_001103461.2 → NP_001096931.1 uncharacterized protein Dmel_CG1889, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001096931.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9W301

Conserved Domains (1) summary

cd00087
Location:117 → 329

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...