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    rpb2 DNA-directed RNA polymerase II complex subunit Rpb2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541446, updated on 14-Nov-2024

    Summary

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    Official Symbol
    rpb2
    Official Full Name
    DNA-directed RNA polymerase II complex subunit Rpb2
    Primary source
    PomBase:SPAC23G3.01
    Locus tag
    SPOM_SPAC23G3.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC521.06
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    Genomic context

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    See rpb2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (850636..854385)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene calcium permease Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ferrichrome synthetase Sib1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and sequence determination of the Schizosaccharomyces pombe rpb2 gene encoding the subunit 2 of RNA polymerase II. Kawagishi M, et al. Nucleic Acids Res, 1993 Feb 11. PMID 8441660, Free PMC Article
    2. Functional organization of two large subunits of the fission yeast Schizosaccharomyces pombe RNA polymerase II. Location of the catalytic sites. Wlassoff WA, et al. J Biol Chem, 1999 Feb 19. PMID 9988759
    3. [Mapping the interaction site of Rpb2 and Rpb3 subunit of fission yeast RNA polymerase II]. Qu Z, et al. Wei Sheng Wu Xue Bao, 2001 Oct. PMID 12552808
    4. RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Kato H, et al. Science, 2005 Jul 15. PMID 15947136
    5. Molecular assembly of RNA polymerase II from the fission yeast Schizosaccharomyces pombe: subunit-subunit contact network involving Rpb5. Miyao T, et al. Genes Cells, 1996 Sep. PMID 9077438

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to DNA-directed 5'-3' RNA polymerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase I activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to RNA polymerase II activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase III activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase IV activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase V activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mitochondrial single subunit type RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables plastid single subunit type RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ribonucleoside binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in siRNA-mediated pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, holoenzyme EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase II complex subunit Rpb2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      850636..854385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018498.3 → NP_593101.2  DNA-directed RNA polymerase II complex subunit Rpb2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593101.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q02061, Q9P7B1, Q9P7T2
      Conserved Domains (1) summary
      PRK08565
      Location:18 → 1204
      PRK08565; DNA-directed RNA polymerase subunit B; Provisional
    Nucleotide Protein
    Heading Accession and Version

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