U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cft2 mRNA processing protein Cft2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539954, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cft2
    Official Full Name
    mRNA processing protein Cft2
    Primary source
    PomBase:SPBC1709.15c
    Locus tag
    SPOM_SPBC1709.15C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cft2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1127954..1130473, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene GTPase-binding protein Rid1 Neighboring gene ribosomal lysine methyltransferase Set10 Neighboring gene ncRNA Neighboring gene peptide N-glycanase Neighboring gene aromatic ring-opening dioxygenase Neighboring gene ncRNA Neighboring gene putative folylpolyglutamate synthase Neighboring gene translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Wittmann S, et al. Nat Commun, 2017 Apr 3. PMID 28367989, Free PMC Article
    2. CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing. Vo TV, et al. Cell Rep, 2019 Jul 2. PMID 31269446, Free PMC Article
    3. A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Roguev A, et al. Mol Cell Proteomics, 2004 Feb. PMID 14617822
    4. The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection. Lemay JF, et al. Genes Dev, 2016 Jul 1. PMID 27401558, Free PMC Article
    5. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of mRNA cleavage and polyadenylation specificity factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mRNA cleavage and polyadenylation specificity factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    mRNA processing protein Cft2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1127954..1130473 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021357.3 → NP_595448.1  mRNA processing protein Cft2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595448.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74740
      Conserved Domains (5) summary
      smart01027
      Location:235 → 361
      Beta-Casp; Beta-Casp domain
      COG1236
      Location:1 → 519
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      pfam07521
      Location:564 → 602
      RMMBL; RNA-metabolizing metallo-beta-lactamase
      pfam13299
      Location:645 → 794
      CPSF100_C; Cleavage and polyadenylation factor 2 C-terminal
      cd16293
      Location:6 → 196
      CPSF2-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 2 and related proteins; MBL-fold metallo-hydrolase domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous