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    guf1 GTPase GUF1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542529, updated on 14-Nov-2024

    Summary

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    Official Symbol
    guf1
    Official Full Name
    GTPase GUF1
    Primary source
    PomBase:SPAC1B3.04c
    Locus tag
    SPOM_SPAC1B3.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See guf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (4931258..4933702, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene Elf1 family transcription elongation factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CCR4-Not complex subunit Not3/5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables membrane scission GTPase motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mitochondrial ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GTPase GUF1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4931258..4933702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020216.3 → NP_594788.2  GTPase GUF1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594788.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13869
      Conserved Domains (6) summary
      cd01890
      Location:59 → 236
      LepA; LepA also known as Elongation Factor 4 (EF4)
      COG0481
      Location:50 → 646
      LepA; Translation elongation factor EF-4, membrane-bound GTPase [Translation, ribosomal structure and biogenesis]
      cd03709
      Location:454 → 533
      lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
      pfam06421
      Location:543 → 646
      LepA_C; GTP-binding protein LepA C-terminus
      cd03699
      Location:244 → 326
      EF4_II; Domain II of Elongation Factor 4 (EF4)
      cd16260
      Location:345 → 420
      EF4_III; Domain III of Elongation Factor 4 (EF4)
    Nucleotide Protein
    Heading Accession and Version

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