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    mti2 translation initiation factor IF-2Mt [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540181, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mti2
    Official Full Name
    translation initiation factor IF-2Mt
    Primary source
    PomBase:SPBC1271.15c
    Locus tag
    SPOM_SPBC1271.15C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mti2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (334066..336676)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutamate N-acetyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe Mti2 and Mti3 act in conjunction during mitochondrial translation initiation. Luo Y, et al. FEBS J, 2019 Nov. PMID 31350787
    2. The Schizosaccharomyces pombe PPR protein Ppr10 associates with a novel protein Mpa1 and acts as a mitochondrial translational activator. Wang Y, et al. Nucleic Acids Res, 2017 Apr 7. PMID 28334955, Free PMC Article
    3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables mitochondrial ribosome binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables translation initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translational initiation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitochondrial translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    translation initiation factor IF-2Mt

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      334066..336676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021043.3 → NP_595135.1  translation initiation factor IF-2Mt [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595135.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59683
      Conserved Domains (6) summary
      cd01887
      Location:172 → 337
      IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
      COG0532
      Location:169 → 686
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
      pfam04760
      Location:96 → 143
      IF2_N; Translation initiation factor IF-2, N-terminal region
      pfam11987
      Location:474 → 572
      IF-2; Translation-initiation factor 2
      cd03692
      Location:590 → 676
      mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
      cd03702
      Location:346 → 442
      IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2
    Nucleotide Protein
    Heading Accession and Version

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