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    spc25 Ndc80 complex subunit Spc25 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539200, updated on 18-Sep-2024

    Summary

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    Official Symbol
    spc25
    Official Full Name
    Ndc80 complex subunit Spc25
    Primary source
    PomBase:SPCC188.04c
    Locus tag
    SPOM_SPCC188.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spc25 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003421.2 (1478061..1481966, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene tRNA-Lys Neighboring gene serine/threonine protein phosphatase PP2A regulatory subunit B-56 Par1 Neighboring gene condensin complex non-SMC subunit Cnd3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene signal recognition particle subunit Srp54

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterisation of the fission yeast Ndc80 complex. Matsuo Y, et al. Protein Expr Purif, 2017 Jul. PMID 28502666, Free PMC Article
    2. Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast. Asakawa H, et al. Mol Biol Cell, 2005 May. PMID 15728720, Free PMC Article
    3. Unraveling the kinetochore nanostructure in Schizosaccharomyces pombe using multi-color SMLM imaging. Virant D, et al. J Cell Biol, 2023 Apr 3. PMID 36705602, Free PMC Article
    4. The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association. Kerres A, et al. Mol Biol Cell, 2004 Dec. PMID 15371542, Free PMC Article
    5. Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores. Heinrich S, et al. EMBO Rep, 2014 Mar. PMID 24477934, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic centromere clustering EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in spindle attachment to meiosis I kinetochore IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Ndc80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Ndc80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IC
    Inferred by Curator
    more info
    		  
    part_of outer kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ndc80 complex subunit Spc25

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1478061..1481966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023198.3 → NP_588208.1  Ndc80 complex subunit Spc25 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588208.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10430
      Conserved Domains (1) summary
      pfam08234
      Location:158 → 226
      Spindle_Spc25; Chromosome segregation protein Spc25
    Nucleotide Protein
    Heading Accession and Version

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