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    RPL24A ribosomal 60S subunit protein L24A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852852, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL24A
    Official Full Name
    ribosomal 60S subunit protein L24A
    Primary source
    SGD:S000002999
    Locus tag
    YGL031C
    See related
    AllianceGenome:SGD:S000002999; FungiDB:YGL031C; VEuPathDB:YGL031C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL30A
    Summary
    Enables RNA binding activity. Involved in translational elongation and translational initiation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL24 (ribosomal protein L24). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL24A in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (437467..437934, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Hop2p Neighboring gene Aga2p Neighboring gene ribosomal 60S subunit protein L30 Neighboring gene Cgr1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A yeast ribosomal protein gene whose intron is in the 5' leader. Mitra G, et al. J Biol Chem, 1984 Jul 25. PMID 6086628
    2. Ribosomal protein L30 is dispensable in the yeast Saccharomyces cerevisiae. Baronas-Lowell DM, et al. Mol Cell Biol, 1990 Oct. PMID 2204809, Free PMC Article
    3. Ribosomal protein eL24, involved in two intersubunit bridges, stimulates translation initiation and elongation. Kisly I, et al. Nucleic Acids Res, 2019 Jan 10. PMID 30407570, Free PMC Article
    4. Yeast ribosomal protein L24 affects the kinetics of protein synthesis and ribosomal protein L39 improves translational accuracy, while mutants lacking both remain viable. Dresios J, et al. Biochemistry, 2000 Jun 20. PMID 10852723
    5. Compensatory mutations in the L30e kink-turn RNA-protein complex. Schweppe JJ, et al. Biochim Biophys Acta, 2009 Jun-Aug. PMID 19460470, Free PMC Article

    See all (127) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational initiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L24A
    NP_011484.1
    • Ribosomal 60S subunit protein L24A; forms two bridges within ribosome, stimulates translation initiation and elongation; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24A has a paralog, RPL24B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      437467..437934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180896.1 → NP_011484.1  TPA: ribosomal 60S subunit protein L24A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011484.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2TBN7, D6VUA7, P04449
      UniProtKB/TrEMBL
      A6ZUG0, A6ZUW3, B3LIP3, C8Z8L1, G2WE63, N1P5K0
      Conserved Domains (1) summary
      pfam01246
      Location:2 → 64
      Ribosomal_L24e; Ribosomal protein L24e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P04449.1

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