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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856125, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000006219
    Locus tag
    YPR015C
    See related
    AllianceGenome:SGD:S000006219; FungiDB:YPR015C; VEuPathDB:YPR015C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable zinc ion binding activity. Involved in DNA damage checkpoint signaling. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (590283..591026, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene translation initiation factor 6 Neighboring gene guanine nucleotide exchange factor DSS4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome profiling of Saccharomyces cerevisiae mutants lacking C2H2 zinc finger proteins. Mao J, et al. BMC Genomics, 2008. PMID 18366603, Free PMC Article
    2. Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library. Youn JY, et al. G3 (Bethesda), 2017 Mar 10. PMID 28122947, Free PMC Article
    3. Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae. Niu W, et al. PLoS Genet, 2008 Jul 11. PMID 18617996, Free PMC Article
    4. Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Finch AJ, et al. Genes Dev, 2011 May 1. PMID 21536732, Free PMC Article
    5. Functional analysis with a barcoder yeast gene overexpression system. Douglas AC, et al. G3 (Bethesda), 2012 Oct. PMID 23050238, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_015340.1
    • Putative zinc finger transcription factor; binds DNA in sequence-specific manner; overexpression causes a cell cycle delay or arrest

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      590283..591026 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184112.1 → NP_015340.1  TPA: uncharacterized protein YPR015C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015340.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W425, Q12531, Q6Q5F4
      UniProtKB/TrEMBL
      A6ZWQ8, B3LL76, B5VTH4, C8ZJ39, N1NVJ3
      Conserved Domains (2) summary
      COG5048
      Location:17 → 247
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00019
      Location:187 → 207
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12531.1

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