QRI1 UDP-N-acetylglucosamine diphosphorylase [Saccharomyces cerevisiae S288C] - Gene

Summary

Go to the top of the page Help

Official Symbol: QRI1
Official Full Name: UDP-N-acetylglucosamine diphosphorylase
Primary source: SGD:S000002261
Locus tag: YDL103C
See related: AllianceGenome:SGD:S000002261; FungiDB:YDL103C; VEuPathDB:YDL103C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: UAP1
Summary: Enables UDP-N-acetylglucosamine diphosphorylase activity. Involved in UDP-N-acetylglucosamine biosynthetic process. Located in cytoplasm and nucleus. Orthologous to human UAP1 (UDP-N-acetylglucosamine pyrophosphorylase 1) and UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See QRI1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 1

Sequence:: Chromosome: IV; NC_001136.10 (275148..276581, complement)

Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables UDP-N-acetylglucosamine diphosphorylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-N-acetylglucosamine diphosphorylase activity	IDA Inferred from Direct Assay more info	PubMed
enables UDP-N-acetylglucosamine diphosphorylase activity	IEA Inferred from Electronic Annotation more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring phosphorus-containing groups	IEA Inferred from Electronic Annotation more info
enables uridylyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in UDP-N-acetylglucosamine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in UDP-N-acetylglucosamine biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in UDP-N-acetylglucosamine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: UDP-N-acetylglucosamine diphosphorylase

NP_010180.1

EC 2.7.7.23

UDP-N-acetylglucosamine pyrophosphorylase; catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001136.10 Reference assembly

Range

275148..276581 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001180162.1 → NP_010180.1 TPA: UDP-N-acetylglucosamine diphosphorylase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_010180.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VRP7, P43123

UniProtKB/TrEMBL

G2WC60

Conserved Domains (1) summary

COG4284
Location:1 → 477

QRI1; UDP-N-acetylglucosamine pyrophosphorylase [Carbohydrate transport and metabolism]