TRP4 anthranilate phosphoribosyltransferase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: TRP4
Official Full Name: anthranilate phosphoribosyltransferase
Primary source: SGD:S000002762
Locus tag: YDR354W
See related: AllianceGenome:SGD:S000002762; FungiDB:YDR354W; VEuPathDB:YDR354W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables anthranilate phosphoribosyltransferase activity. Involved in tryptophan biosynthetic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See TRP4 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 1

Sequence:: Chromosome: IV; NC_001136.10 (1184747..1185889)

Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables anthranilate phosphoribosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables anthranilate phosphoribosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in tryptophan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tryptophan biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in tryptophan biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	HDA more info	PubMed

General protein information

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Preferred Names: anthranilate phosphoribosyltransferase

NP_010641.3

EC 2.4.2.18

Anthranilate phosphoribosyl transferase; transferase of the tryptophan biosynthetic pathway; catalyzes the phosphoribosylation of anthranilate; subject to the general control system of amino acid biosynthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001136.10 Reference assembly

Range

1184747..1185889

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001180662.3 → NP_010641.3 TPA: anthranilate phosphoribosyltransferase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_010641.3

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VSY4, P07285

UniProtKB/TrEMBL

A6ZYV4, B3LFU7, B5VGN6, C7GMI0, C8Z5R5, G2WB92, N1P8P9

Conserved Domains (1) summary

COG0547
Location:3 → 379

TrpD; Anthranilate phosphoribosyltransferase [Amino acid transport and metabolism]