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    spc2 signal peptidase subunit Spc2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541694, updated on 18-Sep-2024

    Summary

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    Official Symbol
    spc2
    Official Full Name
    signal peptidase subunit Spc2
    Primary source
    PomBase:SPAC1071.04c
    Locus tag
    SPOM_SPAC1071.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spc2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3863001..3863504, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene TFIIH regulator Mms19 Neighboring gene ncRNA Neighboring gene protein Sil1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome methytransferase Hpm1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Henry TC, et al. Eukaryot Cell, 2011 Feb. PMID 21169418, Free PMC Article
    2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal peptide processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    part_of signal peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    signal peptidase subunit Spc2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3863001..3863504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019775.1 → NP_594354.1  signal peptidase subunit Spc2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594354.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTQ9
      Conserved Domains (1) summary
      pfam06703
      Location:14 → 162
      SPC25; Microsomal signal peptidase 25 kDa subunit (SPC25)
    Nucleotide Protein
    Heading Accession and Version

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