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    jmj2 histone demethylase Jmj2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543275, updated on 18-Sep-2024

    Summary

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    Official Symbol
    jmj2
    Official Full Name
    histone demethylase Jmj2
    Primary source
    PomBase:SPAC1002.05c
    Locus tag
    SPOM_SPAC1002.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    kdm5
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    Genomic context

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    See jmj2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1804548..1806797, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glucosidase II alpha subunit Gls2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIID complex subunit Taf11 Neighboring gene ncRNA Neighboring gene N-acetyltransferase Ats1 Neighboring gene ncRNA Neighboring gene bouquet formation protein Bqt2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fission yeast Jmj2 reverses histone H3 Lysine 4 trimethylation. Huarte M, et al. J Biol Chem, 2007 Jul 27. PMID 17550896
    2. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article
    3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables histone H3K36 demethylase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables histone H3K4 demethylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    histone demethylase Jmj2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1804548..1806797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018926.2 → NP_593492.1  histone demethylase Jmj2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593492.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9US53
      Conserved Domains (4) summary
      smart00501
      Location:126 → 218
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00545
      Location:59 → 100
      JmjN; Small domain found in the jumonji family of transcription factors
      pfam02373
      Location:455 → 571
      JmjC; JmjC domain, hydroxylase
      pfam02928
      Location:661 → 712
      zf-C5HC2; C5HC2 zinc finger
    Nucleotide Protein
    Heading Accession and Version

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