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    spo9 ER farnesyl pyrophosphate synthetase Erg20 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540933, updated on 14-Nov-2024

    Summary

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    Official Symbol
    spo9
    Official Full Name
    ER farnesyl pyrophosphate synthetase Erg20
    Primary source
    PomBase:SPBC36.06c
    Locus tag
    SPOM_SPBC36.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    erg20
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    Genomic context

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    See spo9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (851808..853237, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cysteine synthase Neighboring gene class 1 histone deacetylase Clr6 Neighboring gene ncRNA Neighboring gene COG complex subunit Cog2 Neighboring gene elongator subunit Iki3 Neighboring gene ncRNA Neighboring gene U2 snRNP-associated protein sap61

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Geranylgeranyl diphosphate synthase in fission yeast is a heteromer of farnesyl diphosphate synthase (FPS), Fps1, and an FPS-like protein, Spo9, essential for sporulation. Ye Y, et al. Mol Biol Cell, 2007 Sep. PMID 17596513, Free PMC Article
    2. A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast. Takami T, et al. PLoS One, 2012. PMID 23145048, Free PMC Article
    3. A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex. Nakase Y, et al. Genetics, 2006 Jun. PMID 16624901, Free PMC Article
    4. Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast. Fang Y, et al. Genes Cells, 2009 Jun. PMID 19486165
    5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables dimethylallyltranstransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dimethylallyltranstransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to farnesyltranstransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables geranyltranstransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables geranyltranstransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in farnesyl diphosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in geranylgeranyl diphosphate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ER farnesyl pyrophosphate synthetase Erg20

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      851808..853237 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021242.3 → NP_595334.1  ER farnesyl pyrophosphate synthetase Erg20 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595334.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59703
      Conserved Domains (1) summary
      pfam00348
      Location:52 → 308
      polyprenyl_synt; Polyprenyl synthetase
    Nucleotide Protein
    Heading Accession and Version

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