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    erg32 C-5 sterol desaturase Erg32 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361266, updated on 18-Sep-2024

    Summary

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    Official Symbol
    erg32
    Official Full Name
    C-5 sterol desaturase Erg32
    Primary source
    PomBase:SPBC27B12.03c
    Locus tag
    SPOM_SPBC27B12.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See erg32 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1324193..1325464, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene double-strand siRNA ribonuclease Eri1 Neighboring gene ERMES complex subunit Mmm1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Mis19 Neighboring gene FAR complex subunit Csc2 Neighboring gene WD repeat protein Crt10, involved in ribosomal RNA decay Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast. Takami T, et al. PLoS One, 2012. PMID 23145048, Free PMC Article
    2. Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe. Iwaki T, et al. Microbiology (Reading), 2008 Mar. PMID 18310029
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables C-5 sterol desaturase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables delta7-sterol 5(6)-desaturase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in ergosterol biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ergosterol biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sterol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum membrane IC
    Inferred by Curator
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C-5 sterol desaturase Erg32

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1324193..1325464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021446.4 → NP_001018791.2  C-5 sterol desaturase Erg32 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018791.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13666
      Conserved Domains (2) summary
      COG3000
      Location:77 → 292
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
      pfam04116
      Location:155 → 280
      FA_hydroxylase; Fatty acid hydroxylase superfamily
    Nucleotide Protein
    Heading Accession and Version

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