GLG2 glycogenin glucosyltransferase GLG2 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: GLG2
Official Full Name: glycogenin glucosyltransferase GLG2
Primary source: SGD:S000003673
Locus tag: YJL137C
See related: AllianceGenome:SGD:S000003673; FungiDB:YJL137C; VEuPathDB:YJL137C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables glycogenin glucosyltransferase activity. Involved in glycogen biosynthetic process. Located in cytoplasm. Orthologous to human GYG2 (glycogenin 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See GLG2 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 1

Sequence:: Chromosome: X; NC_001142.9 (154985..156127, complement)

Chromosome X - NC_001142.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

glycogen synthesis in the absence of glycogenin may rely on an activated glycogen synthase and alternative primers whose synthesis may be controlled by TPS1 or under epigenetic silencing
Title: Glycogen synthesis in the absence of glycogenin in the yeast Saccharomyces cerevisiae.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables glycogenin glucosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycogenin glucosyltransferase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycogen biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in glycogen biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in vacuole	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glycogenin glucosyltransferase GLG2

NP_012398.1

EC 2.4.1.186

Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG2 has a paralog, GLG1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001142.9 Reference assembly

Range

154985..156127 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001181570.1 → NP_012398.1 TPA: glycogenin glucosyltransferase GLG2 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_012398.1

Status: REVIEWED

UniProtKB/Swiss-Prot

A6ZQJ2, D6VW47, P47011

UniProtKB/TrEMBL

B3LPY0, C7GPZ1, C8ZB80

Conserved Domains (1) summary

cd02537
Location:5 → 279

GT8_Glycogenin; Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen