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    his1 ATP phosphoribosyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542720, updated on 18-Sep-2024

    Summary

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    Official Symbol
    his1
    Official Full Name
    ATP phosphoribosyltransferase
    Primary source
    PomBase:SPAC25G10.05c
    Locus tag
    SPOM_SPAC25G10.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See his1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4304356..4305820, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor Zip1 Neighboring gene meiotic recombination protein Rec10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS28 Neighboring gene kinesin-5 family plus-end directed microtubule motor, bimC subfamily Cut7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Schizosaccharomyces pombe his1 and his5 cDNAs. Erickson FL, et al. Yeast, 1995 Feb. PMID 7732725
    2. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. Burr R, et al. J Biol Chem, 2017 Sep 29. PMID 28821619, Free PMC Article
    3. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    4. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
    5. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP phosphoribosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP phosphoribosyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-histidine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-histidine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    ATP phosphoribosyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4304356..4305820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019954.3 → NP_594525.1  ATP phosphoribosyltransferase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594525.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40373
      Conserved Domains (3) summary
      COG0040
      Location:9 → 310
      HisG; ATP phosphoribosyltransferase [Amino acid transport and metabolism]
      cd13592
      Location:10 → 232
      PBP2_HisGL2; The catalytic domain of hexameric long form HisGL2; contains the type 2 periplasmic binding protein fold
      pfam08029
      Location:235 → 307
      HisG_C; HisG, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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