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    apl5 AP-3 adaptor complex subunit Apl5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542857, updated on 18-Sep-2024

    Summary

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    Official Symbol
    apl5
    Official Full Name
    AP-3 adaptor complex subunit Apl5
    Primary source
    PomBase:SPAC144.06
    Locus tag
    SPOM_SPAC144.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See apl5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (4664334..4668408)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent DNA helicase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GTPase Gpn2 Neighboring gene DNAJ domain-containing protein Jac1 Neighboring gene transcription factor TFIIIA Neighboring gene ncRNA Neighboring gene pig-W

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    2. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    3. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to clathrin adaptor activity IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in clathrin-coated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    AP-3 adaptor complex subunit Apl5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4664334..4668408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020096.3 → NP_594667.2  AP-3 adaptor complex subunit Apl5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594667.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTL8
      Conserved Domains (3) summary
      cd00020
      Location:140 → 206
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01602
      Location:21 → 577
      Adaptin_N; Adaptin N terminal region
      sd00044
      Location:212 → 236
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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