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    MRPL27 mitochondrial 54S ribosomal protein YmL27 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852585, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRPL27
    Official Full Name
    mitochondrial 54S ribosomal protein YmL27
    Primary source
    SGD:S000000486
    Locus tag
    YBR282W
    See related
    AllianceGenome:SGD:S000000486; FungiDB:YBR282W; VEuPathDB:YBR282W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    mL41
    Summary
    A structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL41 (mitochondrial ribosomal protein L41). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRPL27 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (768240..768680)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene SCF ubiquitin ligase complex subunit SAF1 Neighboring gene glutamine amidotransferase subunit DUG2 Neighboring gene Ssh1p Neighboring gene metallo-dependent hydrolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The nuclear coded mitoribosomal proteins YmL27 and YmL31 are both essential for mitochondrial function in yeast. Graack HR, et al. Biochimie, 1991 Jun. PMID 1764528
    2. Identification of a motif in BMRP required for interaction with Bcl-2 by site-directed mutagenesis studies. Conde JA, et al. J Cell Biochem, 2012 Nov. PMID 22711503
    3. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. Gruschke S, et al. J Biol Chem, 2010 Jun 18. PMID 20404317, Free PMC Article
    4. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. Kaur J, et al. EMBO Rep, 2011 Sep 1. PMID 21779004, Free PMC Article
    5. The yeast protein Mam33 functions in the assembly of the mitochondrial ribosome. Hillman GA, et al. J Biol Chem, 2019 Jun 21. PMID 31053642, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL27
    NP_009841.1
    • Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      768240..768680
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178630.1 → NP_009841.1  TPA: mitochondrial 54S ribosomal protein YmL27 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009841.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQS7, P36526
      UniProtKB/TrEMBL
      A6ZLM0, B3LMN1, C7GMV0, D3UF29, G2W9T5, N1P9N6
      Conserved Domains (1) summary
      pfam09809
      Location:35 → 131
      MRP-L27; Mitochondrial ribosomal protein L27
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36526.2

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