U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pre6 20S proteasome complex subunit alpha 4 Pre6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540175, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pre6
    Official Full Name
    20S proteasome complex subunit alpha 4 Pre6
    Primary source
    PomBase:SPBC106.16
    Locus tag
    SPOM_SPBC106.16
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mts7
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See pre6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (409475..410766)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene homoserine O-acetyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein uL23

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Lasker K, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307589, Free PMC Article
    2. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Bohn S, et al. Proc Natl Acad Sci U S A, 2010 Dec 7. PMID 21098295, Free PMC Article
    3. The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. Seo HD, et al. J Biol Chem, 2017 Oct 13. PMID 28784663, Free PMC Article
    4. Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes. Leitner A, et al. Proc Natl Acad Sci U S A, 2014 Jul 1. PMID 24938783, Free PMC Article
    5. Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast. Takeda K, et al. Proc Natl Acad Sci U S A, 2010 Feb 23. PMID 20133687, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to endopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome core complex, alpha-subunit complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome core complex, alpha-subunit complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    20S proteasome complex subunit alpha 4 Pre6

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      409475..410766
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021074.3 → NP_595165.1  20S proteasome complex subunit alpha 4 Pre6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595165.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10329
      Conserved Domains (2) summary
      PRK03996
      Location:1 → 232
      PRK03996; proteasome subunit alpha; Provisional
      cd03755
      Location:4 → 211
      proteasome_alpha_type_7; proteasome_alpha_type_7. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.