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    med18 mediator complex subunit Med18 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541925, updated on 18-Sep-2024

    Summary

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    Official Symbol
    med18
    Official Full Name
    mediator complex subunit Med18
    Primary source
    PomBase:SPAC5D6.05
    Locus tag
    SPOM_SPAC5D6.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pmc6; sep11
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    Genomic context

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    See med18 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (1503761..1504867, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene PXA domain protein Pxa1 Neighboring gene UDP-GlcNAc transferase associated protein Alg14 Neighboring gene ncRNA Neighboring gene auxin family transmembrane transporter Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways. Oya E, et al. PLoS Genet, 2013. PMID 23966866, Free PMC Article
    2. The Schizosaccharomyces pombe genes sep10 and sep11 encode putative general transcriptional regulators involved in multiple cellular processes. Szilagyi Z, et al. Mol Genet Genomics, 2002 Dec. PMID 12471453
    3. The involvement of the Schizosaccharomyces pombe sep9/spt8 gene in the regulation of septum cleavage. Batta G, et al. FEMS Yeast Res, 2009 Aug. PMID 19473263
    4. Structure of the Mediator head module. Larivière L, et al. Nature, 2012 Dec 20. PMID 23123849
    5. Cyclin C influences the timing of mitosis in fission yeast. Banyai G, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515143, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in positive regulation of transcription initiation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med18

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1503761..1504867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018796.3 → NP_593364.1  mediator complex subunit Med18 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593364.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14198, Q96VF9
      Conserved Domains (1) summary
      pfam09637
      Location:2 → 203
      Med18; Med18 protein
    Nucleotide Protein
    Heading Accession and Version

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