U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    VID22 Vid22p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851088, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    VID22
    Official Full Name
    Vid22p
    Primary source
    SGD:S000004365
    Locus tag
    YLR373C
    See related
    AllianceGenome:SGD:S000004365; FungiDB:YLR373C; VEuPathDB:YLR373C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables G-quadruplex DNA binding activity. Involved in protein catabolic process in the vacuole. Acts upstream of or within chromatin remodeling. Located in nucleus and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See VID22 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (868662..871367, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Rho family guanine nucleotide exchange factor ROM2 Neighboring gene fatty acid elongase ELO3 Neighboring gene Stp3p Neighboring gene Psy3p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Vid22p, a novel plasma membrane protein, is required for the fructose-1,6-bisphosphatase degradation pathway. Brown CR, et al. J Cell Sci, 2002 Feb 1. PMID 11861771
    2. Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles. Brown CR, et al. J Biol Chem, 2001 Dec 21. PMID 11641409
    3. VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae. Miyata N, et al. Biochem J, 2015 Dec 15. PMID 26443863
    4. DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1. Ribaud V, et al. EMBO J, 2012 Jan 4. PMID 21952045, Free PMC Article
    5. A consensus of core protein complex compositions for Saccharomyces cerevisiae. Benschop JJ, et al. Mol Cell, 2010 Jun 25. PMID 20620961

    See all (74) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VID22 counteracts G-quadruplex-induced genome instability.
      Title: VID22 counteracts G-quadruplex-induced genome instability.
    2. results showed that VID22 is required for transcriptional activation of the PSD2 gene.
      Title: VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae.
    3. Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends.
      Title: Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G-quadruplex DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin remodeling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein catabolic process in the vacuole IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Vid22p
    NP_013477.1
    • G-quadruplex (G4) DNA binding protein; maintains genome integrity by promoting the stability of G4-DNA regions; involved in nucleosome displacement during double-strand break repair; involved in fructose-1,6-bisphosphatase (FBPase) transport from the cytosol to Vid (vacuole import and degradation) vesicles during degradation; glycosylated integral membrane protein of the plasma membrane; localizes to the nucleus; contains a BED-type zinc finger domain and a RNase H-like domain

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      868662..871367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182262.1 → NP_013477.1  TPA: Vid22p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013477.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ10, Q05934
      UniProtKB/TrEMBL
      A7A1Q0, G2WJJ0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05934.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools