U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    sck1 serine/threonine protein kinase S6K family Sck1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542492, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    sck1
    Official Full Name
    serine/threonine protein kinase S6K family Sck1
    Primary source
    PomBase:SPAC1B9.02c
    Locus tag
    SPOM_SPAC1B9.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See sck1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (2402016..2404703, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene GATOR2-SEACAT complex WD repeat subunit Seh1 Neighboring gene ncRNA Neighboring gene nuclear import protein Nxt2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The cyclic AMP/PKA signal pathway is required for initiation of spore germination in Schizosaccharomyces pombe. Hatanaka M, et al. Yeast, 2001 Feb. PMID 11180454
    2. Protein kinase Sck1 is involved in trehalase activation by glucose and nitrogen source in the fission yeast Schizosaccharomyces pombe. Soto T, et al. Microbiology (Reading), 1997 Jul. PMID 9245826
    3. A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity. Chen BR, et al. Exp Gerontol, 2009 Aug. PMID 19409973, Free PMC Article
    4. S. pombe sck2+, a second homologue of S. cerevisiae SCH9 in fission yeast, encodes a putative protein kinase closely related to PKA in function. Fujita M, et al. Curr Genet, 1998 Apr. PMID 9560431
    5. Characterization of tpp1(+) as encoding a main trehalose-6P phosphatase in the fission yeast Schizosaccharomyces pombe. Franco A, et al. J Bacteriol, 2000 Oct. PMID 11004189, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Sck1 negatively regulates PKA activity via binding to Gpa2.
      Title: Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IC
    Inferred by Curator
    more info
    		 PubMed 
    enables lipid binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TORC1 signaling IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in cellular response to heat EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular signal transduction IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of conjugation with cellular fusion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine protein kinase S6K family Sck1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2402016..2404703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019184.3 → NP_593754.1  serine/threonine protein kinase S6K family Sck1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593754.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P50530, Q9UTF3
      Conserved Domains (3) summary
      smart00220
      Location:302 → 563
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05586
      Location:308 → 633
      STKc_Sck1_like; Catalytic domain of Suppressor of loss of cAMP-dependent protein kinase-like Serine/Threonine Kinases
      cl14603
      Location:139 → 294
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.