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    pmh1 transcription factor TFIIK complex ubiquitin-protein ligase E3 subunit, Pmh1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540684, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pmh1
    Official Full Name
    transcription factor TFIIK complex ubiquitin-protein ligase E3 subunit, Pmh1
    Primary source
    PomBase:SPBC776.18c
    Locus tag
    SPOM_SPBC776.18C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mcr1
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    Genomic context

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    See pmh1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003423.3 (3211191..3213716, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene ncRNA Neighboring gene protein Mis20 Neighboring gene ncRNA Neighboring gene rRNA processing protein Rrp7 Neighboring gene ncRNA Neighboring gene kinetochore protein Mis17 Neighboring gene EVE domain (PUA-related) protein, implicated in tRNA metabolism (possible RNA binding domain associated with tRNA methyltransferases) Neighboring gene V-type ATPase inhibitor and disassembly protein linked to MTOR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast. Lee KM, et al. Mol Biol Cell, 2005 Jun. PMID 15829570, Free PMC Article
    2. Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast. Bamps S, et al. Biochem Biophys Res Commun, 2004 Dec 24. PMID 15555586
    3. Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro. Spahr H, et al. J Biol Chem, 2003 Dec 19. PMID 14534314
    4. Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF. Tafforeau L, et al. EMBO J, 2006 Oct 4. PMID 17016471, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity IC
    Inferred by Curator
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleotide-excision repair ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of nucleotide-excision repair factor 3 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIIH holo complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIK complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor TFIIK complex ubiquitin-protein ligase E3 subunit, Pmh1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3211191..3213716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022255.3 → NP_596334.1  transcription factor TFIIK complex ubiquitin-protein ligase E3 subunit, Pmh1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596334.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94684
      Conserved Domains (2) summary
      COG5220
      Location:1 → 309
      TFB3; Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair]
      pfam17121
      Location:10 → 60
      zf-C3HC4_5; Zinc finger, C3HC4 type (RING finger)
    Nucleotide Protein
    Heading Accession and Version

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