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    cam2 myosin I light chain Cam2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542611, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cam2
    Official Full Name
    myosin I light chain Cam2
    Primary source
    PomBase:SPAC29A4.05
    Locus tag
    SPOM_SPAC29A4.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cam2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5137314..5138153, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Prp19 complex subunit, ubiquitin-protein ligase E4 Prp19 Neighboring gene mediator complex subunit Med22 Neighboring gene splicing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Schizosaccharomyces specific protein Neighboring gene ncRNA Neighboring gene pseudouridylate synthase Cbf5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast. Bi J, et al. Dis Model Mech, 2015 Aug 1. PMID 26092123, Free PMC Article
    2. Localization of type I myosin and F-actin to the leading edge region of the forespore membrane in Schizosaccharomyces pombe. Itadani A, et al. Cell Struct Funct, 2006. PMID 17202724
    3. A calmodulin-related light chain from fission yeast that functions with myosin-I and PI 4-kinase. Sammons MR, et al. J Cell Sci, 2011 Jul 15. PMID 21693583
    4. UCS protein Rng3p activates actin filament gliding by fission yeast myosin-II. Lord M, et al. J Cell Biol, 2004 Oct 25. PMID 15504913, Free PMC Article
    5. Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins. Willet AH, et al. Mol Biol Cell, 2023 Oct 1. PMID 37531259, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables enzyme regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables enzyme regulator activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ascospore-type prospore membrane formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle pole body organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell cortex of cell tip EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cortical cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mating projection actin fusion focus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mating projection tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in medial cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of myosin I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin I light chain Cam2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5137314..5138153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020306.3 → NP_594877.1  myosin I light chain Cam2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594877.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14008
      Conserved Domains (3) summary
      COG5126
      Location:1 → 143
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd00051
      Location:79 → 141
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cl08302
      Location:10 → 105
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein
    Heading Accession and Version

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