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    inp53 inositol polyphosphate phosphatase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542329, updated on 18-Sep-2024

    Summary

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    Official Symbol
    inp53
    Official Full Name
    inositol polyphosphate phosphatase
    Primary source
    PomBase:SPAC9G1.10c
    Locus tag
    SPOM_SPAC9G1.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See inp53 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1987258..1991105, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene phospholipase Neighboring gene ncRNA Neighboring gene putative mitotic spindle organizing protein Mzt1 Neighboring gene PAK-like GC kinase Sid1 Neighboring gene ncRNA Neighboring gene mitotic septin Spn4 Neighboring gene tRNA (m1A) methyltransferase complex catalytic subunit Trm61 Neighboring gene Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the contribution of phosphoinositides to medial septation in fission yeast highlights the importance of PI(4,5)P(2) for medial contractile ring anchoring. Snider CE, et al. Mol Biol Cell, 2018 Sep 1. PMID 29975157, Free PMC Article
    2. Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant. Antoine M, et al. iScience, 2020 Jan 24. PMID 31927482, Free PMC Article
    3. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
    4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    5. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphatidylinositol metabolic process IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cortical patch ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    inositol polyphosphate phosphatase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1987258..1991105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018998.3 → NP_593565.1  inositol polyphosphate phosphatase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593565.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14306
      Conserved Domains (3) summary
      smart00128
      Location:787 → 1126
      IPPc; Inositol polyphosphate phosphatase, catalytic domain homologues
      COG5411
      Location:281 → 794
      COG5411; Phosphatidylinositol 5-phosphate phosphatase [Signal transduction mechanisms]
      cd14273
      Location:1161 → 1186
      UBA_TAP-C_like; UBA-like domain found in the NXF family of mRNA nuclear export factors and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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