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    CTO1 Cto1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850373, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CTO1
    Official Full Name
    Cto1p
    Primary source
    SGD:S000000608
    Locus tag
    YCR015C
    See related
    AllianceGenome:SGD:S000000608; FungiDB:YCR015C; VEuPathDB:YCR015C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables thiamine phosphate phosphatase activity. Involved in phosphate ion transport. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CTO1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (141217..142170, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene phosphoglycerate kinase Neighboring gene DNA-directed DNA polymerase IV Neighboring gene ncRNA Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-Cycle Modulation of Transcription Termination Factor Sen1. Mischo HE, et al. Mol Cell, 2018 Apr 19. PMID 29656924, Free PMC Article
    2. Genetic evidence that Ras-like GTPases, Gtr1p, and Gtr2p, are involved in epigenetic control of gene expression in Saccharomyces cerevisiae. Sekiguchi T, et al. Biochem Biophys Res Commun, 2008 Apr 11. PMID 18258182
    3. Uptake of inorganic phosphate is a limiting factor for Saccharomyces cerevisiae during growth at low temperatures. Vicent I, et al. FEMS Yeast Res, 2015 May. PMID 25725023
    4. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
    5. Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. del Alamo M, et al. PLoS Biol, 2011 Jul. PMID 21765803, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables thiamine phosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphate ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Cto1p
    NP_009941.2
    • Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      141217..142170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178728.1 → NP_009941.2  TPA: Cto1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009941.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR23, P25616, Q8NIM3
      UniProtKB/TrEMBL
      A6ZTJ5, B3LU85, B5VEW2, C7GQM6, C8Z4A2, G2WA31, N1P7U7
      Conserved Domains (1) summary
      cl21460
      Location:128 → 237
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25616.2

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