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    vrs1 valine--tRNA (Val) ligase Vrs1/Vas1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540197, updated on 18-Sep-2024

    Summary

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    Official Symbol
    vrs1
    Official Full Name
    valine--tRNA (Val) ligase Vrs1/Vas1
    Primary source
    PomBase:SPBC1709.02c
    Locus tag
    SPOM_SPBC1709.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC1734.18c; ValRS1; vas1
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    Genomic context

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    See vrs1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (1098188..1101489, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene RSC complex bromodomain subunit Rsc4 Neighboring gene SIN3 family co-repressor, Clr6 and Rpd3L histone deacetylase complex subunit Pst3 Neighboring gene ncRNA Neighboring gene chitin synthase-like protein 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe possesses two paralogous valyl-tRNA synthetase genes of mitochondrial origin. Chiu WC, et al. Mol Biol Evol, 2010 Jun. PMID 20106903
    2. Proteome-wide search for PP2A substrates in fission yeast. Bernal M, et al. Proteomics, 2014 Jun. PMID 24634168
    3. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables valine-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables valine-tRNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in cytosolic valyl-tRNA aminoacylation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in valyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    valine--tRNA (Val) ligase Vrs1/Vas1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1098188..1101489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021343.3 → NP_595435.1  valine--tRNA (Val) ligase Vrs1/Vas1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595435.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O75005
      Conserved Domains (4) summary
      cd07962
      Location:728 → 865
      Anticodon_Ia_Val; Anticodon-binding domain of valyl tRNA synthetases
      cd00817
      Location:130 → 728
      ValRS_core; catalytic core domain of valyl-tRNA synthetases
      PTZ00419
      Location:82 → 977
      PTZ00419; valyl-tRNA synthetase-like protein; Provisional
      pfam13603
      Location:313 → 438
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    Nucleotide Protein
    Heading Accession and Version

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